Red. Swollen. Hot. Painful. Signs of inflammation that no
Burlington and Hamilton back pain patient wants to suffer. Spinal Care Clinic
delivers chiropractic services to reduce back pain
by identifying and addressing any associated
inflammation.
INFLAMMATION AND BACK PAIN RELATED
How can you tell if there is
inflammation? Like other issues, researchers search
for ways to measure it. To measure inflammation, researchers look for inflammatory biomarkers, biological markers like tumor
necrosis factor alpha (TNF-α), C-reactive protein (CRP), and interleukin-6,
interleukin-1β, that revealed an increase. Researchers
have uncovered that chronic inflammation increased
cytokine production and stimulated pro-inflammatory
pathways that may lead to non-specific low back pain. (1)
Researchers detected systemic inflammation in chronic LBP and
may influence transition from acute to persistent low back pain. Specifically,
CRP was found elevated in acute low back pain patients versus control patients. TNF was greater in back pain
patients particularly in patients with depression. (2) Since
researchers have already documented that inflammation
is tied to back pain, Spinal Care Clinic knows that
inflammation must be reduced to help in reducing Burlington and Hamilton back pain.
HOW TO STOP INFLAMMATION
Well, first, understand what inflammation does. Researchers
made use of lipopolysaccharide (LPS) to create
intervertebral disc degeneration in trials. They want
to figure out what might potentially decrease
the produced back pain that comes with it
and/or even avoid the degeneration initially
so we humans do not have to be subjected to
low back pain at all! That’s a tough call
though, Spinal Care Clinic knows. But follow
this: researchers used LPS to establish the
degeneration that preceded low back pain. They discovered
that procyanidin B3 (PRO-B3) seen in our diets prevented
the production of inflammatory markers - tumor necrosis factor α (TNF-Α),
interleukin-6 (IL-6), prostaglandin E2 (PGE2) and nitric oxide – associated
with disc degeneration. It also stopped the loss of the
disc’s gelatinous nucleus pulposus cells and structural damage of
its anulus fibrosus (outer rings of disc). What’s all this mean
to researchers looking for a way to stop degenerative
disc degeneration (DDD)? PRO-B3 may be considered as a
treatment agent for intervertebral disc degeneration (IVDD). This is a welcome note for those 80% of us adults who are on track
to get IVDD, a major cause of low back pain. (3) Another current
paper explained that the p38 MAPK inflammatory pathway may be able to delay DDD utilizing the tyrosine
kinase inhibitor, Genistein. (4) That is hopeful
in the treatment of Burlington and Hamilton back pain and inflammation.
Vitamin D FOR INFLAMMATION
Research states that vitamin D deficiency is associated
with low back pain that is stronger in younger women and in those with more
severe deficiency. (5) Vitamin D deficiency is linked to lumbar
disc disease and more severe low back pain in postmenopausal women. (6) Let
us talk about your vitamin D status at your next
Burlington and Hamilton chiropractic appointment.
CONTACT Spinal Care Clinic
Listen to this PODCAST with Dr. Sarah Murrow on The Back Doctors Podcast with Dr. Michael Johnson. In this episode, Dr. Murrow and her patient present how the Cox® Technic System alleviated back pain due to disc bulges.